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Tohoku Univ. Technology:Bioelectric skin patch:T12-177

Disposable patch that does not require external power source and is expected to have drug penetration and cosmetic effect by iontophoresis

"Percutaneous administration" which penetrates the drug from the skin surface is utilized for compresses, nicotine patches, etc.. "Iontophotolysis" which accelerates the penetration of the drug by a weak electric current is utilized for high-speed administration of local anesthetics and penetration enhancement of cosmetic ingredients, etc.. However, generation of iontophotolysis requires power and wiring, and is not suitable for personal use at home. Disposable patches that do not require an external power source by using an enzyme-loaded electrode are expected to have drug penetration and cosmetic effects by iontophoresis.  [Effect] ・No need for an external power source for enzymatic bioelectricity generation ・Disposable because only organic materials are used ・High safety because the maximum current is less than 0.5 mA/cm2 ・Enhanced drug penetration confirmed by a study using pig skin

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